Journal: Addiction (Abingdon, England)

Article Title: Effects of Sex and Alcohol Use on Antiretroviral Therapy Outcomes in Botswana: A Cohort Study

doi: 10.1111/add.13538

Figure Lengend Snippet: Relation between Exposures and Detectable HIV RNA at Month 6

Article Snippet: The primary outcome was composite treatment failure defined as death from any cause, detectable plasma HIV viral load (>25 copies/ml, NucliSENS Easy Q HIV-1, Biomerieux), or loss to follow-up by 6 months.

Techniques:

Journal: Vaccines

Article Title: Longitudinal Antibody Dynamics Following SARS-CoV-2 Viral-Vectored and mRNA Booster Vaccination in Ghanaian Adults

doi: 10.3390/vaccines14040303

Figure Lengend Snippet: Cross-reactive RBD antibody levels before and after booster vaccination. RBD-specific IgG levels against Delta ( A ) and Omicron ( B ) at pre-booster and 3, 6, and 9 months after booster administration. Comparison of RBD-IgG antibody fold change against Wuhan (WH), Delta, and Omicron at months 3, 6, and 9 ( C ). Comparative analysis of RBD IgG levels against Wuhan strain between heterologous ( D , E ) and homologous ( F , G ) booster vaccination. Antibody fold change between heterologous and homologous at month 3 ( H ), month 6 ( I ) and month 9 ( J ). Box plots represent the median and the interquartile range. The whiskers represent 1.5 times the interquartile range. M-V; mRNA prime/viral boost ( n = 20), M-M; mRNA prime/mRNA boost ( n = 45), V-M; viral prime/mRNA boost ( n = 47), V-V; viral prime/viral boost ( n = 69).

Article Snippet: Heterologous boosting with a viral-vectored prime followed by Pfizer mRNA significantly enhanced both peak RBD-IgG levels and durability.

Techniques: Comparison